Category: Missing Heritability

  • Thinking about heritability

    Heritability: The heritability of a trait within a population is the proportion of observable differences in a trait between individuals within a population that is due to genetic differences. Factors including genetics, environment and random chance c…

  • More on the “missing heritability” and epistasis

    Please see Luke Jostins’ posts at Genetic Inference and Genomes Unzipped. Update: Steve Hsu weighs in. He read the supplements! Mad props.

  • “Missing heritability” – interaction edition

    The Pith: A great deal of important medical genetic differences between people may be due to the nature of interactions of genetic variants. If you’ve been reading this blog for a while you know that there is a question in genomics right now as to “missing heritability.” The issue is basically that there are traits…

  • Pygmies are short because nature made them so

    Aka Pygmies The Pith: There has been a long running argument whether Pygmies in Africa are short due to “nurture” or “nature.” It turns out that non-Pygmies with more Pygmy ancestry are shorter and Pygmies with more non-Pygmy …

  • Heritability and genes as causes

    Since the beginning of this weblog (I’ve been writing for eight years) heritability has been a major confusion. Even long time readers misunderstand what I’m trying to get at when I talk about heritability. That’s why posts such as Mr. Luke Jostins‘ are so helpful. I had seen references to a piece online, The Causes of…

Razib Khan