Natural selection in our time
Last month in Nature Reviews Genetics there was a paper, Measuring selection in contemporary human populations, which reviewed data from various surveys in an attempt to adduce the current trajectory of human evolution. The review didn’t find anything revolutionary, but it was interesting to see where we’re at. If you read this weblog you probably […]
The adaptive space of complexity
Evolution means many things to many people. On the one hand some scholars focus on time scales of “billions and billions,” and can ruminate upon the radical variation in body plans across the tree of life. Others put the spotlight on the change in gene frequencies on the scale of years, of Ph.D. programs. While […]
The Bushmen are not primitive! (not necessarily)
To the left is a figure from the 2009 paper The Genetic Structure and History of Africans and African Americans. This paper happens to have excellent coverage of African populations, and the figure is a phylogenetic tree generated from distances between those populations, as well as some non-African ones. I’ve labelled the broad clusters. The […]
To gain pallor is easier than losing it
John Hawks illustrates what can be gained at the intersection of old data and analysis and new knowledge, Quote: Boyd on New World pigmentation clines:
I’m using some statistics out of William Boyd’s 1956 printing of Genetics and the Races of Man[1]. It gives a good accounting of blood group data known more than fifty years […]
Is Christine O’Donnell a kook because she’s a Creationist?
Christine O’Donnell has said a lot of kooky things. Right now people are focusing on her Creationism. Though I’m obviously not a Creationist I think mocking someone for this belief in a political context is somewhat strange: the survey literature is pretty robust that Americans are split down the middle on opinions about evolution. […]
The city that kills you makes you strong!
Over the past day I’ve seen reports in the media of a new paper which claims that long-term urbanization in a region is strongly correlated with genetic variants for disease resistance. I managed to find the paper on Evolution’s website as an accepted manuscript, ANCIENT URBANISATION PREDICTS GENETIC RESISTANCE TO TUBERCULOSIS:
A link between urban living […]
Simple rules for inclusive fitness
With the recent huge furor over the utility of kin selection I’ve been keeping a closer eye on the literature on inclusive fitness. The reason W. D. Hamilton’s original papers in The Journal of Theoretical Biology are highly cited is not some conspiracy, rather, they’re a powerful framework in which one can understand the evolution […]
Raging against the population genetics machine
An interesting readable review in PLoS Genetics taking on population genetics, Frail Hypotheses in Evolutionary Biology:
In conclusion, I return to Michael Lynch’s challenging questions about blind spots and bad wheels in evolutionary biology which motivated this review…Concerning blind spots I have pointed out some limitations of current population genetics. There is too much emphasis on […]
A fly’s life: adventures in experimental evolution
Natural selection happens. It was hypothesized in copious detail by Charles Darwin, and has been confirmed in the laboratory, through observation, and also by inference via the methods of modern genomics. But science is more than broad brushes. We need to drill-down to a more fine-grained level to understand the dynamics with precision and detail, […]
The silver age of altitude adaptation
With all the justified concern about “missing heritability”, the age of human genomics hasn’t been a total bust. As I have observed before in 2005’s excellent book Mutants the evolutionary geneticist Armand M. Leroi asserted that we really didn’t have a good understanding of normal variation of human pigmentation. At the time I think it […]
Leaping to a bigger brain
Years ago an evolutionary biologist mentioned to me almost offhand that with the emergence of genomics and the necessity to master computational techniques a lot of the labor hours which may have gone into a more thorough understanding of specific organisms had gone by the wayside. He believed that his Ph.D. advisor was going to […]
The naked years
When I talk about sexual selection I usually make sure to have an accompanying visual of a peacock to go with the post. But really I could have used a dandy as an illustration, or perhaps in our day & age “The Situation”. Unlike the peacock much of what passes for human “plumage” is not […]
Sexual selection: lowered expectations edition
Sexual selection is, for lack of a better term, a sexy concept. Charles Darwin elaborated on the specific phenomenon of sexual selection in The Descent of Man, and Selection in Relation to Sex. In The Third Chimpanzee Jared Diamond endorsed Darwin’s thesis that sexual selection could explain the origin of human races, as each isolated […]
Not the origin of genome complexity
Over the past decade evolutionary geneticist Mike Lynch has been articulating a model of genome complexity which relies on stochastic factors as the primary motive force by which genome size increases. The argument is articulated in a 2003 paper, and further elaborated in his book The Origins of Genome Architecture. There are several moving parts […]
E. O. Wilson against Hamiltonian inclusive fitness
There is a new paper in Nature which is a full frontal attack on the utility of William D. Hamilton’s inclusive fitness framework in explaining eusociality. Martin A. Nowak, Corina E. Tarnita, & Edward O. Wilson are the authors. Wilson is famous in large part for his authorship of Sociobiology: The New Synthesis, and is […]
A thousand little adaptive platoons
Last week I took an intellectual road trip back nearly a century and explored the historical context and scientific logic by which R. A. Fisher definitively fused Mendelian genetics with quantitative evolutionary biology. In the process he helped birth the field of population genetics. While the genetics which we today are more familiar with begins at […]
The flows and pulses of humanity
Dr. John Hawks points me to a review in BMC Biology, A question of scale: Human migrations writ large and small. It’s short, and of interest for the citations themselves. This a field in flux. One point which I think needs to be emphasized in relation to migration parameters is that there are going to […]
Which population is most genetically distant from Africans?
A comment below:
Razib, I don’t know much about genetics but is it true that these people of Melanesia are among the least related people (even more so than Europeans) to sub-saharan Africans genetically??
This is a common question. The typical scientifically curious intelligent person is generally aware that on the order of 100,000 years ago there […]
Genetics is One: Mendelism and quantitative traits
In the early 20th century there was a rather strange (in hindsight) debate between two groups of biological scientists attempting to understand the basis of inheritance and its relationship to evolutionary processes. The two factions were the biometricians and Mendelians. As indicated by their appellation the Mendelians were partisans of the model of inheritance formulated […]
Hybridization is like sex
One of the major issues which has loomed at the heart of biology since The Origin of Species is why species exist, as well as how species come about. Why isn’t there a perfect replicator which performs all the conversion of energy and matter into biomass on this planet? If there is a God the tree […]